On modelling of bioavailability of drugs in terms of conservation laws
نویسندگان
چکیده
In the text S.Piekarski, M.Rewekant, “On applications of conservation laws in pharmacokinetics”,(arXiv:1208.3847) it has been mentioned that some information on bioavailability and bioequivalence of drugs can be obtained from simulations based on the conservation laws. Here we shortly discuss that possibility starting from the fundamental pharmacokinetic parameter called AUC (Area Under the Curve). The curve is is the profile shape of plasma drug concentration in time intervals after drug administration into organism. Our aim here is to give some information on the subject for the reader with no experience in pharmacokinetics.
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تاریخ انتشار 2013